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    These patients have charged that this manufacturer of Accutane understated the link between Accutane and ulcerative colitis, and did not warn patients or doctors from the increased likelihood of developing this incurable disease. Severe negative effects include the possibility of an pregnant woman using a child having a birth defect, hair loss, hepatitis, pancreatitis, moderate to severe mood changes and menstrual disturbances. Estrogen dominance is really a chronic problem these days.

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